Salvinorin B, kappa-opioid DREADD (KORD) agonist (ab235503)
Key features and details
- A potent and selective κ-opioid DREADD (KORD) agonist
- CAS Number: 92545-30-7
- Purity: > 98%
Soluble in DMSO to 10mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Salvinorin B, kappa-opioid DREADD (KORD) agonist -
Description
A potent and selective κ-opioid DREADD (KORD) agonist -
Alternative names
- (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo 2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
- Divinorin B
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Biological description
A potent and selective κ-opioid DREADD (KORD) agonist. DREADDs are chemogenetic tools widely used to remotely control cellular signaling, neuronal activity and behavior. Displays no analgesic or ataxic effects in wild type mice.
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Purity
> 98% -
General notes
Protect from air and light.
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CAS Number
92545-30-7 -
Chemical structure
Properties
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Chemical name
(2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo 2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
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Molecular weight
390.43 -
Molecular formula
C21H26O7 -
PubChem identifier
11440685 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 10mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC12CCC3C(=O)OC(CC3(C1C(=O)C(CC2C(=O)OC)O)C)C4=COC=C4 -
Source
Synthetic
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Research areas