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Biochemicals Product Range New

SAG Analog (Highly Active), Shh and Smo agonist (ab144353)

Key features and details

  • Cell-permeable Shh and Smo agonist. Potent VEGF activator
  • CAS Number:
  • Purity: > 98%
  • Soluble in DMSO
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    SAG Analog (Highly Active), Shh and Smo agonist
  • Description

    Cell-permeable Shh and Smo agonist. Potent VEGF activator
  • Biological description

    Cell-permeable Shh and Smo agonist (Shh EC50 = 22 µM). Potent VEGF activator. Use in cell proliferation studies. Active in vitro.

    See similar compound
  • Purity

    > 98%
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3,4-Dichloro-N-(cis-4-(methylamino)cyclohexyl)-N-(3-pyridin-4-ylbenzyl)benzo[b]thiophene-2-carboxamide
  • Molecular weight

    524.50
  • Molecular formula

    C28H27Cl2N3OS
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN[C@@H]1CC[C@@H](CC1)N(Cc2cccc(c2)c3ccncc3)C(=O)c5sc4cccc(Cl)c4c5Cl
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Hedgehog signaling
    • Smoothened
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Hedgehog signaling
    • Activators

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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