RS 102221 hydrochloride, 5-HT2C receptor antagonist (ab120982)
Key features and details
- Selective, high affinity 5-HT2C receptor antagonist
- CAS Number: 187397-18-8
- Purity: > 98%
Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
RS 102221 hydrochloride, 5-HT2C receptor antagonist -
Description
Selective, high affinity 5-HT2C receptor antagonist -
Biological description
Selective, high affinity 5-HT2C receptor antagonist (pKi = 8.4). Displays approximately 100-fold selectivity over the 5-HT2A and 5-HT2B subtypes and > 100-fold selectivity over other 5-HT receptors, α- and β-adrenergic and muscarinic ACh receptors.
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Purity
> 98% -
CAS Number
187397-18-8 -
Chemical structure
Properties
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Chemical name
N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-
oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-benzenesulfonamide hydrochloride -
Molecular weight
649.08 -
Molecular formula
C27H31F3N4O7S.HCl -
Storage instructions
Store at room temperature (desiccating conditions). -
Solubility overview
Soluble in DMSO to 100 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.FC(F)(F)c1ccc(cc1)S(=O)(=O)Nc2cc(c(OC)cc2OC)C(=O)CCCCN4CCC3(NC(=O)NC3=O)CC4 -
Source
Synthetic
