RepSox, TGF-beta type 1 receptor inhibitor (ab142139)
Key features and details
- Selective TGF-β type 1 receptor inhibitor. Cell-permeable.
- CAS Number: 446859-33-2
- Purity: > 98%
- Soluble in ethanol to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
RepSox, TGF-beta type 1 receptor inhibitor -
Description
Selective TGF-β type 1 receptor inhibitor. Cell-permeable. -
Alternative names
- ALK5 Inhibitor II
- E-616452
- SJN 2511
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Purity
> 98% -
CAS Number
446859-33-2 -
Chemical structure
Properties
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Chemical name
2-[5-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine -
Molecular weight
287.32 -
Molecular formula
C17H13N5 -
PubChem identifier
449054 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4 -
Source
Synthetic
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Research areas
