Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Rat RBP4 protein (ab109146)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: DDDDK tag N-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Rat RBP4 protein
    See all RBP4 proteins and peptides

  • Purity

    > 90 % SDS-PAGE.
    ab109146 is 0.2µm filtered

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    P04916

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Rat

    • Predicted molecular weight

      23 kDa including tags

    • Amino acids

      19 to 201

    • Tags

      DDDDK tag N-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab109146 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid

    • Additional notes

      Working aliquots are stable for up to 3 months when stored at -20°C.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

      pH: 7.20
      Constituent: PBS

    General Info

    • Alternative names

      • OTTHUMP00000020114
      • OTTHUMP00000020115
      • OTTHUMP00000020116
      • Plasma retinol binding protein 4
      • Plasma retinol-binding protein
      • Plasma retinol-binding protein(1-176)
      • PRBP
      • PRO2222
      • RBP
      • RBP4
      • RDCCAS
      • RET4_HUMAN
      • Retinol binding protein 4
      • Retinol binding protein 4 interstitial
      • Retinol binding protein 4 plasma
      see all

    • Function

      Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

    • Involvement in disease

      Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.

    • Sequence similarities

      Belongs to the calycin superfamily. Lipocalin family.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab109146? Please let us know so that we can cite the reference in this datasheet.

ab109146 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.20
    Constituent: PBS

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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