• Product name

  Recombinant Human RBP4 protein
  See all RBP4 proteins and peptides

• Purity

  > 95 % SDS-PAGE.
  Endotoxin:

• Expression system

  Escherichia coli

• Protein length

  Full length protein

• Animal free

  No

• Nature

  Recombinant

• • Species

    Human

  • Sequence

    MSWWHHHHHH NWNIPTTQDT TERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMK YWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSE RNLL

• Alternative names

  • OTTHUMP00000020114
  • OTTHUMP00000020115
  • OTTHUMP00000020116

  • Plasma retinol binding protein 4
  • Plasma retinol-binding protein
  • Plasma retinol-binding protein(1-176)
  • PRBP
  • PRO2222
  • RBP
  • RBP4
  • RDCCAS
  • RET4_HUMAN
  • Retinol binding protein 4
  • Retinol binding protein 4 interstitial
  • Retinol binding protein 4 plasma

  see all

• Function

  Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

• Involvement in disease

  Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.

• Sequence similarities

  Belongs to the calycin superfamily. Lipocalin family.

• Cellular localization

  Secreted.

• Target information above from: UniProt accession P02753 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt