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Signal Transduction Growth Factors/Hormones Hormones

Recombinant Rat Leptin protein (ab646)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant Rat Leptin protein
    See all Leptin proteins and peptides
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Rat
    • Sequence

      Rat Leptin is a 16.2 kDa protein containing 147 amino acid residues: MVPIHKVQDD TKTLIKTIVT RINDISHTQS VSARQRVTGL DFIPGLHPIL SLSKM DQTLAVYQQILTSLP SQNVLQIAHD LENLRDLLHL LAFSKSCSLP Q TRGLQKPES LDGVLEASLYSTEVVALSRL QGSLQDILQQ LDLSPEC
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab646 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

      • Reconstitution
        Reconstitute with 1ml pure water.

      General Info

      • Alternative names

        • FLJ94114
        • LEP
        • LEP_HUMAN
        • LEPD
        • Leptin
        • Leptin (murine obesity homolog)
        • Leptin (obesity homolog, mouse)
        • Leptin Murine Obesity Homolog
        • Leptin Precursor Obesity Factor
        • OB
        • Obese protein
        • Obese, mouse, homolog of
        • Obesity
        • Obesity factor
        • Obesity homolog mouse
        • Obesity Murine Homolog Leptin
        • OBS
        • OTTHUMP00000212285
        see all
      • Function

        May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
      • Involvement in disease

        Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
      • Sequence similarities

        Belongs to the leptin family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P41159 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab646? Please let us know so that we can cite the reference in this datasheet.

    ab646 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • FLJ94114
      • LEP
      • LEP_HUMAN
      • LEPD
      • Leptin
      • Leptin (murine obesity homolog)
      • Leptin (obesity homolog, mouse)
      • Leptin Murine Obesity Homolog
      • Leptin Precursor Obesity Factor
      • OB
      • Obese protein
      • Obese, mouse, homolog of
      • Obesity
      • Obesity factor
      • Obesity homolog mouse
      • Obesity Murine Homolog Leptin
      • OBS
      • OTTHUMP00000212285
      see all
    • Function

      May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
    • Involvement in disease

      Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
    • Sequence similarities

      Belongs to the leptin family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P41159 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Alternative products to Recombinant Rat Leptin protein (ab646)

    •  
    • Product image

      Recombinant human Leptin protein (Animal Free) (ab222359)

      Applications: FuncS, SDS-PAGE

    •  
    • Recombinant human Leptin protein (ab168049)

      Applications: FuncS, SDS-PAGE

    •  
    • Product image

      Recombinant Human Leptin protein (ab51273)

      Applications: SDS-PAGE, WB

    •  
    • Recombinant Mouse Leptin protein (ab9750)

      Applications: FuncS, SDS-PAGE

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