Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Escherichia coli
Endotoxin level:
Active: Yes
Suitable for: SDS-PAGE, Functional Studies, HPLC

Product name

Recombinant mouse Uteroglobin protein (Active)
See all Uteroglobin proteins and peptides
Biological activity

Fully biologically active when compared to standard. The ED₅₀ as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of >200 IU/m.
Endotoxin level
Expression system

Escherichia coli
Accession

Q06318
Protein length

Full length protein
Animal free

No
Nature

Recombinant
- Species
  
  Mouse
- Sequence
  
  DICPGFLQVLEALLMESESGYVASLKPFNPGSDLQNAGTQLKRLVDTLPQ ETRINIMKLTEKILTSPLCKQDLRF
- Predicted molecular weight
  
  17 kDa
- Amino acids
  
  22 to 96
- Additional sequence information
  
  Full length mature chain without signal peptide.

Our Abpromise guarantee covers the use of ab243209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

SDS-PAGE

Functional Studies

HPLC
Form

Lyophilized
Concentration information loading...

Stability and Storage

Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Constituents: 0.87% Sodium chloride, Phosphate Buffer

0.2 µm filtered

This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at = -20 °C. Further dilutions should be made in appropriate buffered solutions.

Alternative names
- Blastokinin
- CC10
- CC16
- CCPBP
- CCSP
- Clara cell phospholipid binding protein
- Clara cell phospholipid-binding protein
- Clara cell specific 10 kD protein
- Clara cells 10 kDa secretory protein
- OTTHUMP00000236107
- SCGB1A1
- Secretoglobin family 1A member 1
- Secretoglobin, family 1A, member 1 (uteroglobin)
- UG
- UGB
- UP-1
- UP1
- Urinary protein 1
- Urine protein 1
- UTER_HUMAN
- Uteroglobin
see all
Function

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Tissue specificity

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).
Sequence similarities

Belongs to the secretoglobin family.
Cellular localization

Secreted.
Target information above from: UniProt accession P11684 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols