Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Mouse TIM 1 protein (Fc Chimera) (ab215016)

Key features and details

  • Expression system: CHO cells
  • Purity: >= 98% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Mouse TIM 1 protein (Fc Chimera)
    See all TIM 1 proteins and peptides

  • Purity

    >= 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    CHO cells

  • Accession

    Q5QNS5-2

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      YVEVKGVVGHPVTLPCTYSTYRGITTTCWGRGQCPSSACQNTLIWTNGHR VTYQKSSRYNLKGHISEGDVSLTIENSVESDSGLYCCRVEIPGWFNDQKV TFSLQVKPEIPTRPPRRPTTTRPTATGRPTTISTRSTHVPTSTRVSTSTP PTSTHTWTHKPDWNGTVTSSGDTWSNHTEAIPPGKPQKNPT

    • Predicted molecular weight

      21 kDa

    • Amino acids

      22 to 212

    • Additional sequence information

      Fused to the N-terminus of the Fc region of human IgG1 (NP_001160104.1).

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab215016 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

        Constituent: 100% PBS

        Lyophilised from 0.2µm filtered solution.

      • Reconstitution
        Reconstitute with 100 µL sterile water. Add 1X PBS to the desired protein concentration.

      General Info

      • Alternative names

        • CD365
        • HAVCR
        • HAVCR 1
        • HAVcr-1
        • Havcr1
        • Hepatitis A virus cellular receptor 1
        • Kidney injury molecule 1
        • KIM 1
        • KIM-1
        • T cell immunoglobin domain and mucin domain protein 1
        • T cell immunoglobulin mucin family member 1
        • T cell immunoglobulin mucin receptor 1
        • T-cell immunoglobulin and mucin domain-containing protein 1
        • T-cell membrane protein 1
        • TIM
        • TIM-1
        • TIM1
        • TIMD 1
        • TIMD-1
        • TIMD1
        • TIMD1_HUMAN
        see all

      • Function

        May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.

      • Tissue specificity

        Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.

      • Sequence similarities

        Belongs to the immunoglobulin superfamily. TIM family.
        Contains 1 Ig-like V-type (immunoglobulin-like) domain.

      • Cellular localization

        Membrane.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab215016? Please let us know so that we can cite the reference in this datasheet.

    ab215016 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • CD365
      • HAVCR
      • HAVCR 1
      • HAVcr-1
      • Havcr1
      • Hepatitis A virus cellular receptor 1
      • Kidney injury molecule 1
      • KIM 1
      • KIM-1
      • T cell immunoglobin domain and mucin domain protein 1
      • T cell immunoglobulin mucin family member 1
      • T cell immunoglobulin mucin receptor 1
      • T-cell immunoglobulin and mucin domain-containing protein 1
      • T-cell membrane protein 1
      • TIM
      • TIM-1
      • TIM1
      • TIMD 1
      • TIMD-1
      • TIMD1
      • TIMD1_HUMAN
      see all

    • Function

      May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.

    • Tissue specificity

      Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.

    • Sequence similarities

      Belongs to the immunoglobulin superfamily. TIM family.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Cellular localization

      Membrane.
    • Information by UniProt

    Images

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