Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Mouse PD-L2 protein (ab214612)

Key features and details

  • Expression system: CHO cells
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Mouse PD-L2 protein
    See all PD-L2 proteins and peptides

  • Purity

    > 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    CHO cells

  • Accession

    Q9WUL5

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      LFTVTAPKEVYTVDVGSSVSLECDFDRRECTELEGIRASLQKVENDTSLQ SERATLLEEQLPLGKALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKV KASYMRIDTRILEVPGTGEVQLTCQARGYPLAEVSWQNVSVPANTSHIRT PEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRMEPKVPR

    • Amino acids

      20 to 219

    • Additional sequence information

      The extracellular domain of mouse PD-L2 (aa 20-219) is fused to the N-terminus of the Fc region of mouse IgG2a.

    • Specifications

    Our Abpromise guarantee covers the use of ab214612 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Stable for 12 months at -20°C.

      Constituent: 99% PBS

      Lyophilized from 0.2 µm filtered solution.

    • Reconstitution
      Reconstitute at 100 µg/mL in sterile PBS. Working aliquots are stable for up to 3 months when stored at -20°C.

    General Info

    • Alternative names

      • B7 dendritic cell molecule
      • B7-DC
      • B7DC
      • bA574F11.2
      • Btdc
      • Butyrophilin B7 DC
      • Butyrophilin B7-DC
      • Butyrophilin B7DC
      • CD 273
      • CD273
      • CD273 antigen
      • MGC142238
      • MGC142240
      • PD 1 ligand 2
      • PD L2
      • PD-1 ligand 2
      • PD-L2
      • PD1 ligand 2
      • PD1L2_HUMAN
      • PDCD 1 ligand 2
      • PDCD1 ligand 2
      • PDCD1L2
      • Pdcd1lg2
      • PDL 2
      • PDL2
      • Programmed cell death 1 ligand 2
      • Programmed death ligand 2
      see all

    • Function

      Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

    • Tissue specificity

      Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.

    • Sequence similarities

      Belongs to the immunoglobulin superfamily. BTN/MOG family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Cellular localization

      Secreted; Cell membrane and Endomembrane system.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab214612? Please let us know so that we can cite the reference in this datasheet.

ab214612 has not yet been referenced specifically in any publications.

Preparation and Storage

  • B7 dendritic cell molecule
  • B7-DC
  • B7DC

Images

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