Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Mouse MD2 protein (Fc Chimera) (ab276978)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: Fc tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Mouse MD2 protein (Fc Chimera)
    See all MD2 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q9JHF9

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      MLPFILFSTL LSPILTESEK QQWFCNSSDA IISYSYCDHL KFPISISSEP CIRLRGTNGF VHVEFIPRGN LKYLYFNLFI SVNSIELPKR KEVLCHGHDD DYSFCRALKG ETVNTSIPFS FEGILFPKGH YRCVAEAIAG DTEEKLFCLN FTIIHRRDVN

    • Predicted molecular weight

      43 kDa including tags

    • Molecular weight information

      The recombinant mouse LY96/Fc is a disulfide-linked homodimer. The reduced monomer comprises 383 amino acids and has a predicted molecular mass of 43.4 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions.

    • Amino acids

      1 to 160

    • Tags

      Fc tag C-Terminus

    • Additional sequence information

      Fc region of human IgG1.Predicted N-terminus: Glu 19.

    • Specifications

    Our Abpromise guarantee covers the use of ab276978 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • ESOP 1
      • ESOP-1
      • ESOP1
      • LY 96
      • Ly-96
      • LY96
      • LY96_HUMAN
      • Lymphocyte antigen 96
      • md 2
      • MD 2 protein
      • MD2 protein
      • Myeloid differentiation protein 2
      • Protein MD 2
      • Protein MD-2
      • Protein MD2
      see all

    • Function

      Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.

    • Post-translational
      modifications

      N-glycosylated; high-mannose.

    • Cellular localization

      Secreted > extracellular space.
    • Information by UniProt

Images

  • SDS-PAGE - Recombinant Mouse MD2 protein (Fc Chimera) (ab276978)
    SDS-PAGE - Recombinant Mouse MD2 protein (Fc Chimera) (ab276978)
    SDS-PAGE analysis of ab276978

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab276978? Please let us know so that we can cite the reference in this datasheet.

ab276978 has not yet been referenced specifically in any publications.

Preparation and Storage

  • ESOP 1
  • ESOP-1
  • ESOP1

Images

  • SDS-PAGE - Recombinant Mouse MD2 protein (Fc Chimera) (ab276978)
    SDS-PAGE - Recombinant Mouse MD2 protein (Fc Chimera) (ab276978)
    SDS-PAGE analysis of ab276978

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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