Piroxicam, cyclooxygenase-1 (COX-1) inhibitor (ab141110)
Key features and details
- Reversible, selective cyclooxygenase-1 (COX-1) inhibitor
- CAS Number: 36322-90-4
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Piroxicam, cyclooxygenase-1 (COX-1) inhibitor -
Description
Reversible, selective cyclooxygenase-1 (COX-1) inhibitor -
Biological description
Reversible, selective cyclooxygenase-1 (COX-1) inhibitor. Shows 8-fold greater activity against COX-1 than COX-2 (IC50 values are 0.76 and 8.99 μM for COX-1 and COX-2, respectively).
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Purity
> 99% -
CAS Number
36322-90-4 -
Chemical structure
Properties
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Chemical name
4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide -
Molecular weight
331.35 -
Molecular formula
C15H13N3O4S -
PubChem identifier
54676228 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OC=2c1ccccc1S(=O)(=O)N(C)C=2C(=O)Nc3ccccn3 -
Source
Synthetic
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Research areas
- Epigenetics and Nuclear Signaling
- Transcription
- Domain Families
- HLH / Leucine Zipper
- Helix-Turn-Helix
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
