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Immunology Innate Immunity Chemokines Alpha Chemokines (CXC)

Recombinant mouse MCP3 protein (ab9912)

Key features and details

  • Expression system: Escherichia coli
  • Purity: >= 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant mouse MCP3 protein
    See all MCP3 proteins and peptides
  • Biological activity

    Determined by its ability to chemoattract BaF3 cells expressing human CCR2 receptor using a
    concentration range of 300-500 ng/mL.

  • Purity

    >= 98 % SDS-PAGE.
    = 98% by SDS-PAGE gel and HPLC analyses.s.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q03366
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      QPDGPNASTCCYVKKQKIPKRNLKSYRRITSSRCPWEAVIFKTKKGMEVC AEAHQKWVEEAIAYLDMKTPTPKP
    • Predicted molecular weight

      11 kDa
    • Amino acids

      24 to 97
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9912 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • C-C motif chemokine 7
        • Ccl7
        • CCL7_HUMAN
        • Chemokine CC motif ligand 7
        • FIC
        • MARC
        • MCP-3
        • Monocyte chemoattractant protein 3
        • Monocyte chemotactic protein 3
        • NC28
        • RP23-350G1.4
        • SCYA6
        • SCYA7
        • Small-inducible cytokine A7
        see all
      • Function

        Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.
      • Post-translational
        modifications

        O-glycosylated.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P80098 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab9912? Please let us know so that we can cite the reference in this datasheet.

    ab9912 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C-C motif chemokine 7
      • Ccl7
      • CCL7_HUMAN
      • Chemokine CC motif ligand 7
      • FIC
      • MARC
      • MCP-3
      • Monocyte chemoattractant protein 3
      • Monocyte chemotactic protein 3
      • NC28
      • RP23-350G1.4
      • SCYA6
      • SCYA7
      • Small-inducible cytokine A7
      see all
    • Function

      Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications

      O-glycosylated.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P80098 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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