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Immunology Innate Immunity Chemokines Alpha Chemokines (CXC)

Recombinant mouse MCP3 protein (Active) (ab243263)

Recombinant mouse MCP3 protein (Active) (ab243263)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies, HPLC

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Description

  • Product name

    Recombinant mouse MCP3 protein (Active)
    See all MCP3 proteins and peptides
  • Biological activity

    Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 100-300 ng/ml.

  • Purity

    > 95 % SDS-PAGE.
    >95% as determined by HPLC.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q03366
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      QPDGPNASTCCYVKKQKIPKRNLKSYRRITSSRCPWEAVIFKTKKGMEVC AEAHQKWVEEAIAYLDMKTPTPKP
    • Predicted molecular weight

      9 kDa
    • Amino acids

      24 to 97
    • Additional sequence information

      Full-length mature chain lacking the signal peptide.
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab243263 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

        HPLC

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        Constituent: PBS

        0.2 µm filtered

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      General Info

      • Alternative names

        • C-C motif chemokine 7
        • Ccl7
        • CCL7_HUMAN
        • Chemokine CC motif ligand 7
        • FIC
        • MARC
        • MCP-3
        • Monocyte chemoattractant protein 3
        • Monocyte chemotactic protein 3
        • NC28
        • RP23-350G1.4
        • SCYA6
        • SCYA7
        • Small-inducible cytokine A7
        see all
      • Function

        Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.
      • Post-translational
        modifications

        O-glycosylated.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P80098 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Images

    • SDS-PAGE - Recombinant mouse MCP3 protein (Active) (ab243263)
      SDS-PAGE - Recombinant mouse MCP3 protein (Active) (ab243263)
      SDS-PAGE analysis of ab243263

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab243263? Please let us know so that we can cite the reference in this datasheet.

    ab243263 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C-C motif chemokine 7
      • Ccl7
      • CCL7_HUMAN
      • Chemokine CC motif ligand 7
      • FIC
      • MARC
      • MCP-3
      • Monocyte chemoattractant protein 3
      • Monocyte chemotactic protein 3
      • NC28
      • RP23-350G1.4
      • SCYA6
      • SCYA7
      • Small-inducible cytokine A7
      see all
    • Function

      Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications

      O-glycosylated.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P80098 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant mouse MCP3 protein (Active) (ab243263)
      SDS-PAGE - Recombinant mouse MCP3 protein (Active) (ab243263)
      SDS-PAGE analysis of ab243263

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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