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Recombinant mouse IL-11 protein (Animal Free) (ab187212)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant mouse IL-11 protein (Animal Free)
    See all IL-11 proteins and peptides
  • Biological activity

    Determined by the dose-dependent proliferation of mouse IL-11 and is typically less then 2 ng/mL.

  • Purity

    > 98 % SDS-PAGE.
    Protein Content and Purity (typically = 98%) determined by: Reducing and Non-reducing SDS-PAGE.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    P47873
  • Protein length

    Full length protein
  • Animal free

    Yes
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
    • Predicted molecular weight

      19 kDa
    • Amino acids

      22 to 199
    • Additional sequence information

      ab187212 is a non-glycosylated protein, containing 179 amino acids.
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab187212 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Additional notes

        This product is produced with no animal-derived raw products, animal free equipment and animal free protocols.

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.

      General Info

      • Alternative names

        • Adipogenesis inhibitory factor
        • AGIF
        • IL 11
        • IL-11
        • Il11
        • IL11_HUMAN
        • Interleukin 11
        • Interleukin-11
        • Oprelvekin
        see all
      • Function

        Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
      • Sequence similarities

        Belongs to the IL-6 superfamily.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P20809 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab187212? Please let us know so that we can cite the reference in this datasheet.

    ab187212 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Adipogenesis inhibitory factor
      • AGIF
      • IL 11
      • IL-11
      • Il11
      • IL11_HUMAN
      • Interleukin 11
      • Interleukin-11
      • Oprelvekin
      see all
    • Function

      Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
    • Sequence similarities

      Belongs to the IL-6 superfamily.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P20809 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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