• Product name

  Recombinant mouse IL-11 protein
  See all IL-11 proteins and peptides

• Biological activity

  The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁵ units/mg.

• Purity

  > 95 % SDS-PAGE.
  Purity is greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  

• Expression system

  Escherichia coli

• Protein length

  Full length protein

• Animal free

  No

• Nature

  Recombinant

• • Species

    Mouse

  • Sequence

    M -PGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL

  • Amino acids

    22 to 199

• Alternative names

  • Adipogenesis inhibitory factor
  • AGIF
  • IL 11

  • IL-11
  • Il11
  • IL11_HUMAN
  • Interleukin 11
  • Interleukin-11
  • Oprelvekin

  see all

• Function

  Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.

• Sequence similarities

  Belongs to the IL-6 superfamily.

• Cellular localization

  Secreted.

• Target information above from: UniProt accession P20809 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt