Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant mouse IL-11 protein (ab200279)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 97% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies, HPLC

Description

  • Product name

    Recombinant mouse IL-11 protein
    See all IL-11 proteins and peptides

  • Biological activity

    The ED50 as determined by the dose-dependant stimulation of the proliferation of mouse T11 was found to be less than 2.0 ng/mL, corresponding to a specific activity of 5 x 105 IU/mg.

  • Purity

    > 97 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P47873

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      MPGPPAGSPRVSSDPRADLDSAVLLTRSLLADTRQLAAQMRDKFPADGDH SLDSLPTLAMSAGTLGSLQLPGVLTRLRVDLMSYLRHVQWLRRAGGPSLK TLEPELGALQARLERLLRRLQLLMSRLALPQAAPDQPVIPLGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL

    • Predicted molecular weight

      19 kDa

    • Amino acids

      22 to 199

    • Additional sequence information

      Mature protein without signal peptide.

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab200279 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

        HPLC

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        pH: 7.40
        Constituent: 100% PBS

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL.

      General Info

      • Alternative names

        • Adipogenesis inhibitory factor
        • AGIF
        • IL 11
        • IL-11
        • Il11
        • IL11_HUMAN
        • Interleukin 11
        • Interleukin-11
        • Oprelvekin
        see all

      • Function

        Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.

      • Sequence similarities

        Belongs to the IL-6 superfamily.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab200279? Please let us know so that we can cite the reference in this datasheet.

    ab200279 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Adipogenesis inhibitory factor
      • AGIF
      • IL 11
      • IL-11
      • Il11
      • IL11_HUMAN
      • Interleukin 11
      • Interleukin-11
      • Oprelvekin
      see all

    • Function

      Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.

    • Sequence similarities

      Belongs to the IL-6 superfamily.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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