Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Mouse GITR protein (ab185843)

Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus, Fc tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituent: 100% PBS

    Lyophilized from a 0.2 µM filtered solution.

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in 1X PBS. It is not recommended to reconstitute to a concentration less than 100 µg/ml. After reconstitution aliquot and store at

    General Info

    • Alternative names

      • Activation inducible TNFR family receptor
      • Activation-inducible TNFR family receptor
      • AITR
      • CD357
      • GITR
      • GITR D
      • GITR-D
      • GITRD
      • Glucocorticoid induced TNFR related protein
      • glucocorticoid-induced tnf receptor ligand
      • glucocorticoid-induced tnf receptors ligand
      • Glucocorticoid-induced TNFR-related protein
      • TNF receptor superfamily activation inducible protein
      • TNFRSF 18
      • TNFRSF18
      • TNR18_HUMAN
      • Tumor necrosis factor receptor superfamily member 18
      • Tumor necrosis factor receptor superfamily member 18 precursor
      see all

    • Function

      Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

    • Tissue specificity

      Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.

    • Sequence similarities

      Contains 3 TNFR-Cys repeats.

    • Cellular localization

      Secreted and Cell membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Mouse GITR protein (ab185843)
      SDS-PAGE - Recombinant Mouse GITR protein (ab185843)

      MK: Molecular weight markers

      R: Reduced

      NR: Non-reduced

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

References (0)

Publishing research using ab185843? Please let us know so that we can cite the reference in this datasheet.

ab185843 has not yet been referenced specifically in any publications.

Images

  • SDS-PAGE - Recombinant Mouse GITR protein (ab185843)
    SDS-PAGE - Recombinant Mouse GITR protein (ab185843)

    MK: Molecular weight markers

    R: Reduced

    NR: Non-reduced

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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