Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant mouse Eotaxin protein (ab201417)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 96% SDS-PAGE
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE, HPLC

Description

  • Product name

    Recombinant mouse Eotaxin protein
    See all Eotaxin proteins and peptides

  • Biological activity

    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000 ng/ml.

  • Purity

    > 96 % SDS-PAGE.
    > 96 % by HPLC analysis

  • Expression system

    Escherichia coli

  • Accession

    P48298

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      HPGSIPTSCCFIMTSKKIPNTLLKSYKRITNNRCTLKAIVFKTRLGKEIC ADPKKKWVQDATKHLDQKLQTPKP

    • Predicted molecular weight

      8 kDa

    • Amino acids

      24 to 97

    • Additional sequence information

      This product is for the mature full length protein. The signal peptide is not included. A single non-glycosylated polypeptide chain.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituent: 100% PBS

    Lyophilized from a 0.2 µM filtered solution.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Briefly centrifuge prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at

    General Info

    • Alternative names

      • C-C motif chemokine 11
      • CCL 11
      • CCL11
      • CCL11_HUMAN
      • chemokine (C-C motif) ligand 11
      • Chemokine C C motif ligand 11
      • Chemokine CC Motif Ligand 11
      • Chemokine ligand 11
      • Eosinophil chemotactic protein
      • Eotaxin
      • eotaxin-1
      • MGC22554
      • SCYA 11
      • SCYA11
      • Small inducible cytokine A11
      • Small inducible cytokine subfamily A (Cys Cys) member 11
      • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
      • Small inducible cytokine subfamily A member 11
      • Small-inducible cytokine A11
      see all

    • Function

      In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Post-translational
      modifications

      O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

References (0)

Publishing research using ab201417? Please let us know so that we can cite the reference in this datasheet.

ab201417 has not yet been referenced specifically in any publications.

Images

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