Recombinant mouse CSF-1-R protein (Fc Chimera Active) (ab220450)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Preparation and Storage
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Alternative names
- C FMS
- CD 115
- CD115
see all -
Function
Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34. -
Tissue specificity
Expressed in bone marrow and in differentiated blood mononuclear cells. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant mouse CSF-1-R protein (Fc Chimera Active) (ab220450)
SDS-PAGE analysis of ab220450 under reducing (lane 1) and no-reducing (lane 2) conditions, stained overnight with coomassie blue. The protein migrates as 100-130 kDa under reducing and 260 kDa under non-reducing conditions.
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Functional Studies - Recombinant mouse CSF-1-R protein (Fc Chimera Active) (ab220450)Immobilized mouse M-CSF protein at 2μg/mL (100 μL/well) can bind ab220450 with a linear range of 0.3-12.8 ng/mL.
