Recombinant cynomolgus monkey CSF-1-R protein (Fc Chimera Active) (ab220532)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE, ELISA
Preparation and Storage
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Alternative names
- C FMS
- CD 115
- CD115
see all -
Function
Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34. -
Tissue specificity
Expressed in bone marrow and in differentiated blood mononuclear cells. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
Images
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Functional Studies - Recombinant Cynomolgus monkey CSF-1-R protein (Fc Chimera) (ab220532)
Immobilized human M-CSF, His Tag at 5 μg/mL (100 μL/well) can bind ab220532 with a linear range of 1-39 ng/mL.
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Functional Studies - Recombinant Cynomolgus monkey CSF-1-R protein (Fc Chimera) (ab220532)Immobilized biotinylated human MCSF, His,Avitag (ab246167) at 2 μg/mL (100 μL/well) on streptavidin precoated (0.2 μg/well) plate, can bind ab220532 with a linear range of 1-39 ng/mL.
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SDS-PAGE - Recombinant Cynomolgus monkey CSF-1-R protein (Fc Chimera) (ab220532)SDS-PAGE - Recombinant Cynomolgus monkey Axl protein (Fc Chimera) (ab220532).
The gel was stained overnight with Coomassie Blue.
As a result of glycosylation, the protein migrates as 110-125 kDa under reducing (R) conditions and 200- 240 kDa under non-reducing (NR) conditions.
