Recombinant mouse CNTF protein (ab200253)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, SDS-PAGE, Functional Studies
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Product name
Recombinant mouse CNTF protein
See all CNTF proteins and peptides -
Biological activity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using Human TF-1 cells is less than 30 ng/ml, corresponding to a specific activity of > 3.3 × 104 IU/mg.
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Purity
> 95 % SDS-PAGE.
Purity > 95 % by SDS-PAGE and HPLC analyses. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
AFAEQSPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNISLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LTLQVSAFAY QLEELMALLE QKVPEKEADG MPVTIGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HHMGISAHES HYGAKQM -
Predicted molecular weight
23 kDa -
Amino acids
2 to 198
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Preparation and Storage
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Alternative names
- Ciliary neurotrophic factor
- CNTF
- CNTF_HUMAN
- HCNTF
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Function
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. -
Tissue specificity
Nervous system. -
Sequence similarities
Belongs to the CNTF family. -
Cellular localization
Cytoplasm. - Information by UniProt
