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Immunology Innate Immunity Macrophage / Inflamm.

Recombinant Mouse BD-3 protein (Animal Free) (ab245951)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant Mouse BD-3 protein (Animal Free)
    See all BD-3 proteins and peptides
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q9WTL0
  • Protein length

    Full length protein
  • Animal free

    Yes
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      KKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
    • Predicted molecular weight

      5 kDa
    • Amino acids

      23 to 63
    • Additional sequence information

      Full length mature protein without the signal and propeptide.
  • Specifications

    Our Abpromise guarantee covers the use of ab245951 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituent: 0.1% Trifluoroacetic acid

    • Reconstitution
      Reconstitute in water to 0.1 - 1.0 mg/ml.

    General Info

    • Alternative names

      • BD 3
      • BD-3
      • BD3
      • beta 103
      • Beta defensin 103A
      • Beta defensin 103A precursor
      • Beta defensin 3
      • Beta-defensin 103
      • Beta-defensin 3
      • D103A_HUMAN
      • DEF B3
      • DEFB 103
      • DEFB 103A
      • DEFB 3
      • DEFB-3
      • DEFB103
      • DEFB103A
      • DEFB103B
      • DEFB3
      • Defensin
      • Defensin beta 103A
      • Defensin beta 3
      • Defensin like protein
      • Defensin-like protein
      • HBD 3
      • hBD-3
      • HBD3
      • HBP 3
      • HBP3
      • mBD3
      see all
    • Function

      Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
    • Tissue specificity

      Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
    • Sequence similarities

      Belongs to the beta-defensin family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P81534 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab245951? Please let us know so that we can cite the reference in this datasheet.

    ab245951 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • BD 3
    • BD-3
    • BD3

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Alternative products to Recombinant Mouse BD-3 protein (Animal Free) (ab245951)

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      Applications: BL

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      Applications: FuncS, HPLC, SDS-PAGE

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