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Immunology Innate Immunity Macrophage / Inflamm.

Recombinant human BD-3 protein (ab50059)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

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Description

  • Product name

    Recombinant human BD-3 protein
    See all BD-3 proteins and peptides
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Amino acids

      1 to 45
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50059 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized
      • Additional notes

        Previously labelled as beta Defensin 3. 

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        Reconstitute to 1mg/ml using sterile water.

      General Info

      • Alternative names

        • BD 3
        • BD-3
        • BD3
        • beta 103
        • Beta defensin 103A
        • Beta defensin 103A precursor
        • Beta defensin 3
        • Beta-defensin 103
        • Beta-defensin 3
        • D103A_HUMAN
        • DEF B3
        • DEFB 103
        • DEFB 103A
        • DEFB 3
        • DEFB-3
        • DEFB103
        • DEFB103A
        • DEFB103B
        • DEFB3
        • Defensin
        • Defensin beta 103A
        • Defensin beta 3
        • Defensin like protein
        • Defensin-like protein
        • HBD 3
        • hBD-3
        • HBD3
        • HBP 3
        • HBP3
        • mBD3
        see all
      • Function

        Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
      • Tissue specificity

        Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
      • Sequence similarities

        Belongs to the beta-defensin family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P81534 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab50059? Please let us know so that we can cite the reference in this datasheet.

    ab50059 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • BD 3
      • BD-3
      • BD3
      • beta 103
      • Beta defensin 103A
      • Beta defensin 103A precursor
      • Beta defensin 3
      • Beta-defensin 103
      • Beta-defensin 3
      • D103A_HUMAN
      • DEF B3
      • DEFB 103
      • DEFB 103A
      • DEFB 3
      • DEFB-3
      • DEFB103
      • DEFB103A
      • DEFB103B
      • DEFB3
      • Defensin
      • Defensin beta 103A
      • Defensin beta 3
      • Defensin like protein
      • Defensin-like protein
      • HBD 3
      • hBD-3
      • HBD3
      • HBP 3
      • HBP3
      • mBD3
      see all
    • Function

      Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
    • Tissue specificity

      Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
    • Sequence similarities

      Belongs to the beta-defensin family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P81534 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Alternative products to Recombinant human BD-3 protein (ab50059)

    •  
    • Human BD-3 peptide (ab42250)

      Applications: BL

    •  
    • Recombinant Mouse BD-3 protein (Animal Free) (ab245951)

      Applications: HPLC, SDS-PAGE

    •  
    • Recombinant human BD-3 protein (ab200245)

      Applications: FuncS, HPLC, SDS-PAGE

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