Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human YKT6 protein (ab172846)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag N-Terminus
  • Suitable for: HPLC, SDS-PAGE

Description

  • Product name

    Recombinant Human YKT6 protein

  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Supplied as a 0.2 µM filtered solution.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    O15498

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVER SSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDE FSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETK IILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIMLD LQSR

    • Predicted molecular weight

      22 kDa

    • Amino acids

      1 to 198

    • Tags

      His tag N-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab172846 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituent: 0.61% Tris

      50mM

    General Info

    • Alternative names

      • R SNARE
      • SNARE protein Ykt6
      • Synaptobrevin homolog YKT6
      • YKT 6
      • YKT6
      • YKT6 S. cerevisiae homolog of
      • YKT6 v SNARE homolog
      • YKT6 v SNARE protein
      • YKT6_HUMAN
      see all

    • Function

      Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

    • Sequence similarities

      Belongs to the synaptobrevin family.
      Contains 1 longin domain.
      Contains 1 v-SNARE coiled-coil homology domain.

    • Domain

      The longin domain regulates palmitoylation and membrane targeting.

    • Post-translational
      modifications

      Palmitoylated; catalyzes its own palmitoylation. Palmitoylation is required for Golgi targeting.
      Farnesylation is required for Golgi targeting.

    • Cellular localization

      Cytoplasm > cytosol. Cytoplasmic vesicle membrane. Golgi apparatus membrane. Probably cycles through vesicles between Golgi and endosomes.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab172846? Please let us know so that we can cite the reference in this datasheet.

ab172846 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituent: 0.61% Tris

    50mM

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