Recombinant human PLA2G7 protein (ab204758)
Key features and details
- Expression system: HEK 293 cells
- Endotoxin level:
- Active: Yes
- Suitable for: HPLC, SDS-PAGE, Functional Studies
Preparation and Storage
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Alternative names
- Platelet-activating factor acetylhydrolase precursor
- 1 alkyl 2 acetylglycerophosphocholine esterase
- 1-alkyl-2-acetylglycerophosphocholine esterase
see all -
Function
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids. -
Tissue specificity
Plasma. -
Involvement in disease
Platelet-activating factor acetylhydrolase deficiency
Asthma
Atopic hypersensitivity -
Sequence similarities
Belongs to the AB hydrolase superfamily. Lipase family. -
Cellular localization
Secreted, extracellular space. - Information by UniProt
