Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: HEK 293 cells
Endotoxin level:
Active: Yes
Suitable for: HPLC, SDS-PAGE, Functional Studies

Alternative names
- Platelet-activating factor acetylhydrolase precursor
- 1 alkyl 2 acetylglycerophosphocholine esterase
- 1-alkyl-2-acetylglycerophosphocholine esterase
- 2 acetyl 1 alkylglycerophosphocholine esterase
- 2-acetyl-1-alkylglycerophosphocholine esterase
- EC 3.1.1.47 PAF acetylhydrolase PAF 2-acylhydrolase LDL associated phospholipase A2
- Group VIIA phospholipase A2
- Group-VIIA phospholipase A2
- gVIIA PLA2
- gVIIA-PLA2
- LDL associated phospholipase A2
- LDL PLA(2)
- LDL PLA2
- LDL-associated phospholipase A2
- LDL-PLA(2)
- Lipoprotein associated phospholipase A2
- LP PLA2
- PAF 2 acylhydrolase
- PAF 2 acylhydrolase LDL associated phospholipase A2
- PAF 2-acylhydrolase
- PAF acetylhydrolase
- PAFA_HUMAN
- PAFAD
- PAFAH
- Phospholipase A2, group VII (platelet activating factor acetylhydrolase, plasma)
- PLA2G7
- Platelet activating factor acetylhydrolase
- Platelet activating factor acetylhydrolase 2
- Platelet-activating factor acetylhydrolase
see all
Function

Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Tissue specificity

Plasma.
Involvement in disease

Platelet-activating factor acetylhydrolase deficiency
Asthma
Atopic hypersensitivity
Sequence similarities

Belongs to the AB hydrolase superfamily. Lipase family.
Cellular localization

Secreted, extracellular space.
Target information above from: UniProt accession Q13093 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

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Recombinant human PLA2G7 protein (ab204758)

Key features and details

Preparation and Storage

Alternative names

Function

Tissue specificity

Involvement in disease

Sequence similarities

Cellular localization

Images

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