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Signal Transduction Cytoskeleton / ECM Extracellular Matrix Structures Bone

Recombinant Human Osteocalcin protein (ab152232)

Recombinant Human Osteocalcin protein (ab152232)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Wheat germ
  • Suitable for: SDS-PAGE, WB, ELISA

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Description

  • Product name

    Recombinant Human Osteocalcin protein
    See all Osteocalcin proteins and peptides
  • Expression system

    Wheat germ
  • Accession

    P02818
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      YLYQWLGAPVPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV
    • Predicted molecular weight

      31 kDa including tags
    • Amino acids

      52 to 100

Preparation and Storage

  • Alternative names

    • BGLAP
    • BGP
    • Bone gamma carboxyglutamate (gla) protein
    • Bone gamma carboxyglutamate gla protein osteocalcin
    • Bone gamma carboxyglutamate protein
    • Bone Gla protein
    • Gamma carboxyglutamic acid containing protein
    • Gamma-carboxyglutamic acid-containing protein
    • OC
    • OCN
    • OSTCN_HUMAN
    • Osteocalcin
    • OTTHUMP00000016586
    • PMF1
    see all
  • Function

    Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
  • Sequence similarities

    Belongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.
  • Post-translational
    modifications

    Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P02818 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Osteocalcin protein (ab152232)
    SDS-PAGE - Recombinant Human Osteocalcin protein (ab152232)
    12.5% SDS-PAGE analysis of ab152232 stained with Coomassie Blue.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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