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Neuroscience Neurology process Notch Pathway

Recombinant Human NT2NL protein (Fc Chimera) (ab276626)

Recombinant Human NT2NL protein (Fc Chimera) (ab276626)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: Fc tag N-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human NT2NL protein (Fc Chimera)
    See all NT2NL proteins and peptides
  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    P0DPK3
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MPALRPALLW ALLALWLCCA TPAHALQCRD GYEPCVNEGM CVTYHNGTGY CKCPEGFLGE YCQHRDPCEK NRCQNGGTCV AQAMLGKATC RCASGFTGED CQYSTSHPCF VSRPCLNGGT CHMLSRDTYE CTCQVGFTGK ECQWTDACLS HPCANGSTCT TVANQFSCKC LTGFTGQKCE TDVNECDIPG HCQHGGICLN LPGSYQCQCL QGFTGQYCDS LYVPCAPSPC VNGGTC
    • Predicted molecular weight

      53 kDa including tags
    • Molecular weight information

      The recombinant human NOTCH2NL consists of 472 amino acids and predicts a molecular mass of 52.5 kDa.
    • Amino acids

      1 to 236
    • Tags

      Fc tag N-Terminus
    • Additional sequence information

      Fc region of mouse IgG1. Predicted N-terminus: Asp.
  • Specifications

    Our Abpromise guarantee covers the use of ab276626 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • N2N
      • Notch 2 N terminal like
      • Notch homolog 2 (Drosophila) N-terminal like
      • Notch homolog 2 N-terminal-like protein
      • NOTCH2NL
      • NT2NL_HUMAN
      • OTTHUMP00000015593
      see all
    • Function

      May function in the Notch signaling pathway and regulate neutrophil differentiation.
    • Tissue specificity

      Widely expressed with higher levels in leukocytes and lymph nodes.
    • Sequence similarities

      Belongs to the NOTCH family.
      Contains 6 EGF-like domains.
    • Post-translational
      modifications

      Cleaved by ELANE.
    • Cellular localization

      Secreted. Cytoplasm.
    • Target information above from: UniProt accession Q7Z3S9 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant Human NT2NL protein (ab276626)
    SDS-PAGE - Recombinant Human NT2NL protein (ab276626)
    SDS-PAGE analysis of ab276626

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276626? Please let us know so that we can cite the reference in this datasheet.

    ab276626 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • N2N
    • Notch 2 N terminal like
    • Notch homolog 2 (Drosophila) N-terminal like

    Images

    • SDS-PAGE - Recombinant Human NT2NL protein (ab276626)
      SDS-PAGE - Recombinant Human NT2NL protein (ab276626)
      SDS-PAGE analysis of ab276626

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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