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Neuroscience Neurology process Growth and Development Neurotrophins

Recombinant human Neurotrophin 3 protein (Animal Free) (ab217474)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Active: Yes
  • Suitable for: SDS-PAGE, HPLC, Functional Studies

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Description

  • Product name

    Recombinant human Neurotrophin 3 protein (Animal Free)
    See all Neurotrophin 3 proteins and peptides
  • Biological activity

    The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.

  • Purity

    > 98 % SDS-PAGE.
    > 98 % HPLC.
  • Expression system

    Escherichia coli
  • Accession

    P20783
  • Protein length

    Full length protein
  • Animal free

    Yes
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
    • Predicted molecular weight

      14 kDa
    • Amino acids

      139 to 257
    • Additional sequence information

      This product is for the mature full length protein. The signal peptide and propeptide are not included.

Preparation and Storage

  • Alternative names

    • HDNF
    • MGC129711
    • Nerve growth factor 2
    • Neurotrophic factor
    • Neurotrophin 3 precursor
    • Neurotrophin-3
    • Neurotrophin3
    • NGF 2
    • NGF-2
    • NGF2
    • NT 3
    • NT-3
    • NT3
    • NTF 3
    • NTF3
    • NTF3_HUMAN
    see all
  • Function

    Seems to promote the survival of visceral and proprioceptive sensory neurons.
  • Tissue specificity

    Brain and peripheral tissues.
  • Sequence similarities

    Belongs to the NGF-beta family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P20783 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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