Recombinant human KGF protein (ab9601)
Key features and details
- Expression system: Escherichia coli
- Active: Yes
- Suitable for: CellDiff, Functional Studies, SDS-PAGE
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Product name
Recombinant human KGF protein
See all KGF proteins and peptides -
Biological activity
Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8).
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Expression system
Escherichia coli -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
22 kDa
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Preparation and Storage
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Alternative names
- FGF 7
- FGF-7
- Fgf7
see all -
Function
Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. -
Tissue specificity
Epithelial cell. -
Sequence similarities
Belongs to the heparin-binding growth factors family. -
Cellular localization
Secreted. - Information by UniProt
Images
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Cell differentiation - Recombinant human KGF protein (ab9601) This image is courtesy of Emily Moorefield, Wake Forest Institute for Regenerative Medicine, NC, USADefinitive endoderm derived from culturing human embryonic stem cells (HUES4) with Inhibin beta a (ab50051) and Wnt3a (ab81484) was further differentiated to gut tube endoderm as described in Kroon et al, Nat Biotechnol. (2008). KGF (ab9601) was added to the media to direct differentiation towards gut tube endoderm. This image was taken 3 days after addition of KGF, where the gut tube endoderm marker TCF2 (ab59118 in green) is present. Dapi staining is shown in blue. Magnification: 200x. Negative controls of fluorescently conjugated secondary antibodies only showed no staining.
