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Cancer Tumor immunology Cytokines Interleukins

Recombinant human IL36 beta/IL-1F8 protein (ab138901)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, HPLC, SDS-PAGE

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Description

  • Product name

    Recombinant human IL36 beta/IL-1F8 protein
    See all IL36 beta/IL-1F8 proteins and peptides
  • Biological activity

    Measured by its ability to induce IL8 production by Human PBMCs.
  • Purity

    > 98 % SDS-PAGE.
    Purity: > 98% by SDS-PAGE gel and HPLC analyses.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q9NZH7-2
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE
    • Predicted molecular weight

      17 kDa
    • Amino acids

      5 to 157
  • Specifications

    Our Abpromise guarantee covers the use of ab138901 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      HPLC

      SDS-PAGE

    • Form

      Lyophilized
    • Additional notes

      Measured by its ability to induce IL8 production by Human PBMCs.

      Previously labelled as IL36 beta.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      Constituent: 0.16% Sodium phosphate

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA).

    General Info

    • Alternative names

      • 2310043N20Rik
      • Family of interleukin 1 eta
      • FIL1
      • FIL1 (ETA)
      • FIL1 eta
      • FIL1H
      • FILI-(ETA)
      • IL 1F8
      • IL 1F8 (FIL1 eta
      • IL 1H2
      • IL-1 eta
      • IL-1F8
      • IL-1H2
      • IL1 ETA
      • IL1F8
      • IL1F8 (Canonical product IL 1F8a)
      • IL1F8_HUMAN
      • IL1H2
      • IL36 beta
      • IL36B
      • Interleukin 1 family, member 8
      • Interleukin 1 family, member 8 (eta)
      • Interleukin 1 homolog 2
      • Interleukin 1 Superfamily e
      • Interleukin 36 beta
      • Interleukin-1 eta
      • Interleukin-1 family member 8
      • Interleukin-1 homolog 2
      • MGC126880
      • MGC126882
      • OTTMUSP00000012797
      • RP23-176J12.1
      see all
    • Tissue specificity

      Expression at low levels in tonsil, bone marrow, heart, placenta, lung, testis and colon but not in other tissues or in any hematopoietic cell lines.
    • Sequence similarities

      Belongs to the IL-1 family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession Q9NZH7 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab138901? Please let us know so that we can cite the reference in this datasheet.

    ab138901 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • 2310043N20Rik
    • Family of interleukin 1 eta
    • FIL1

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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