Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human IL-7 protein (Fc Chimera) (ab214592)

Key features and details

  • Expression system: CHO cells
  • Purity: >= 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human IL-7 protein (Fc Chimera)
    See all IL-7 proteins and peptides

  • Biological activity

    The Fc-protein was measured in a cell proliferation assay using antibody against CD3-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is typically 10-100ng/ml.

  • Purity

    >= 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    CHO cells

  • Accession

    P13232

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      DCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDAN KEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRK PAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTK EH

    • Predicted molecular weight

      17 kDa

    • Amino acids

      26 to 177

    • Additional sequence information

      This product is for the mature full length protein. The signal peptide is not included. It is fused to the N-terminus of the Fc portion of a mutant Human IgG1 (AAH47698.1).

    • Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab214592 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Stable for 12 months at -20°C.

      Constituent: PBS

      0.2µm-filtered

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Reconstitute vial in 50 µL sterile water. Add 1X PBS to the desired protein concentration. Working aliquots are stable for up to 3 months when stored at -20°C.

    General Info

    • Alternative names

      • IL 7
      • IL-7
      • Il7
      • IL7_HUMAN
      • Interleukin 7
      • Interleukin-7
      • LP-1
      • Lymphopoietin 1
      see all

    • Function

      Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.

    • Sequence similarities

      Belongs to the IL-7/IL-9 family.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab214592? Please let us know so that we can cite the reference in this datasheet.

ab214592 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Stable for 12 months at -20°C.

    Constituent: PBS

    0.2µm-filtered

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute vial in 50 µL sterile water. Add 1X PBS to the desired protein concentration. Working aliquots are stable for up to 3 months when stored at -20°C.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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