Recombinant Human IL-2 Receptor alpha protein (ab56232)
Key features and details
- Expression system: Baculovirus
- Purity: > 95% SDS-PAGE
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant Human IL-2 Receptor alpha protein
See all IL-2 Receptor alpha proteins and peptides -
Purity
> 95 % SDS-PAGE.
> 95% by SDS-PAGE and HPLC analyses Endotoxin level: -
Expression system
Baculovirus -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human
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Preparation and Storage
-
Alternative names
- Interleukin 2 receptor alpha chain
- CD25
- CD25 antigen
see all -
Function
Receptor for interleukin-2. -
Involvement in disease
Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. -
Sequence similarities
Contains 2 Sushi (CCP/SCR) domains. -
Cellular localization
Membrane. - Information by UniProt
