Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human IL-19 protein (Active) (ab243761)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE, HPLC

Description

  • Product name

    Recombinant human IL-19 protein (Active)
    See all IL-19 proteins and peptides

  • Biological activity

    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-20Rα and human IL-20Rβ co-transfected murine BaF3 pro-B cells is less than 1.5 ng/ml, corresponding to a specific activity of >6.7x105 IU/mg.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q9UHD0

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      LRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLE TLQIIKPLDV CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYM QKTLRQCQEQ RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFL AWINKNHEVM SSA

    • Predicted molecular weight

      18 kDa

    • Amino acids

      25 to 177

    • Additional sequence information

      Full length mature chain without signal peptide.

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab243761 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

        HPLC

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        Constituent: PBS

        0.2 µm filtered

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20degC. Further dilutions should be made in appropriate buffered solutions.

      General Info

      • Alternative names

        • IL 10C
        • IL 19
        • IL-19
        • Il19
        • IL19_HUMAN
        • Interleukin 19
        • Interleukin-19
        • MDA1
        • Melanoma differentiation-associated protein-like protein
        • NG.1
        • ZMDA1
        see all

      • Function

        May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.

      • Sequence similarities

        Belongs to the IL-10 family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Images

    • SDS-PAGE - Recombinant human IL-19 protein (Active) (ab243761)
      SDS-PAGE - Recombinant human IL-19 protein (Active) (ab243761)
      SDS Page analysis of IL-19 with ab243761.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab243761? Please let us know so that we can cite the reference in this datasheet.

    ab243761 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • IL 10C
      • IL 19
      • IL-19
      • Il19
      • IL19_HUMAN
      • Interleukin 19
      • Interleukin-19
      • MDA1
      • Melanoma differentiation-associated protein-like protein
      • NG.1
      • ZMDA1
      see all

    • Function

      May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.

    • Sequence similarities

      Belongs to the IL-10 family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant human IL-19 protein (Active) (ab243761)
      SDS-PAGE - Recombinant human IL-19 protein (Active) (ab243761)
      SDS Page analysis of IL-19 with ab243761.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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