Recombinant Human IL-18BP protein (Fc Chimera) (ab276260)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human IL-18BP protein (Fc Chimera)
See all IL-18BP proteins and peptides -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MRHNWTPDLS PLWVLLLCAH VVTLLVRATP VSQTTTAATA SVRSTKDPCP SQPPVFPAAK QCPALEVTWP EVEVPLNGTL SLSCVACSRF PNFSILYWLG NGSFIEHLPG RLWEGSTSRE RGSTGTQLCK ALVLEQLTPA LHSTNFSCVL VDPEQVVQRH VVLAQLWAGL RATLPPTQEA LPSSHSSPQQ QG -
Predicted molecular weight
44 kDa including tags -
Molecular weight information
The recombinant human IL18BP consists of 402 amino acids and predicts a molecular mass of 44.4 kDa. -
Amino acids
3 to 194 -
Tags
Fc tag C-Terminus -
Additional sequence information
Fc region of human IgG1.Predicted N-terminus: Thr 29.
Specifications
Our Abpromise guarantee covers the use of ab276260 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- I18BP_HUMAN
- IL-18BP
- IL18 binding protein
see all -
Function
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. -
Tissue specificity
Strongly expressed in heart, lung, placenta and spleen. -
Sequence similarities
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276260 has not yet been referenced specifically in any publications.
Preparation and Storage
- I18BP_HUMAN
- IL-18BP
- IL18 binding protein