Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human IL-18BP protein (Fc Chimera) (ab276260)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: Fc tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human IL-18BP protein (Fc Chimera)
    See all IL-18BP proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    O95998

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MRHNWTPDLS PLWVLLLCAH VVTLLVRATP VSQTTTAATA SVRSTKDPCP SQPPVFPAAK QCPALEVTWP EVEVPLNGTL SLSCVACSRF PNFSILYWLG NGSFIEHLPG RLWEGSTSRE RGSTGTQLCK ALVLEQLTPA LHSTNFSCVL VDPEQVVQRH VVLAQLWAGL RATLPPTQEA LPSSHSSPQQ QG

    • Predicted molecular weight

      44 kDa including tags

    • Molecular weight information

      The recombinant human IL18BP consists of 402 amino acids and predicts a molecular mass of 44.4 kDa.

    • Amino acids

      3 to 194

    • Tags

      Fc tag C-Terminus

    • Additional sequence information

      Fc region of human IgG1.Predicted N-terminus: Thr 29.

    • Specifications

    Our Abpromise guarantee covers the use of ab276260 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • I18BP_HUMAN
      • IL-18BP
      • IL18 binding protein
      • IL18 BP
      • IL18 BPa
      • IL18BP
      • IL18BPa
      • Interleukin 18 binding protein
      • Interleukin-18-binding protein
      • MC51L 53L 54L homolog gene product
      • Tadekinig alfa
      • Tadekinig-alfa
      see all

    • Function

      Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.

    • Tissue specificity

      Strongly expressed in heart, lung, placenta and spleen.

    • Sequence similarities

      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

    • Cellular localization

      Secreted.
    • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human IL-18BP protein (ab276260)
    SDS-PAGE - Recombinant Human IL-18BP protein (ab276260)
    SDS-PAGE analysis of ab276260

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab276260? Please let us know so that we can cite the reference in this datasheet.

ab276260 has not yet been referenced specifically in any publications.

Preparation and Storage

  • I18BP_HUMAN
  • IL-18BP
  • IL18 binding protein

Images

  • SDS-PAGE - Recombinant Human IL-18BP protein (ab276260)
    SDS-PAGE - Recombinant Human IL-18BP protein (ab276260)
    SDS-PAGE analysis of ab276260

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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