3MB-PP1, tyrosine kinase inhibitor (ab143754)
Key features and details
- Specific tyrosine kinase inhibitor.
- CAS Number: 956025-83-5
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
3MB-PP1, tyrosine kinase inhibitor -
Description
Specific tyrosine kinase inhibitor. -
Alternative names
- 1-(1,1-Dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-Pyrazolo[3,4-d]pyrimidin-4-
- 3-MB-PP1
- 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine
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Biological description
Uniquely specific bulky tyrosine kinase inhibitor which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
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CAS Number
956025-83-5 -
Chemical structure
Properties
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Chemical name
4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine -
Molecular weight
295.38 -
Molecular formula
C17H21N5 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
