Recombinant human IL-13 protein (Animal Free) (ab217420)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, Functional Studies, SDS-PAGE
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Product name
Recombinant human IL-13 protein (Animal Free)
See all IL-13 proteins and peptides -
Biological activity
Determined by its ability to stimulate the proliferation of Human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥1 x 106 units/mg.
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Purity
> 98 % SDS-PAGE.
> 98% by HPLC analysis. -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
Yes -
Nature
Recombinant -
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Species
Human -
Sequence
MSPGPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAAL ESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKD LLLHLKKLFREGRFN -
Predicted molecular weight
13 kDa -
Amino acids
33 to 146
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Preparation and Storage
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Alternative names
- Allergic rhinitis
- ALRH
- BHR 1
see all -
Function
Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. -
Involvement in disease
Allergic rhinitis -
Sequence similarities
Belongs to the IL-4/IL-13 family. -
Cellular localization
Secreted. - Information by UniProt
