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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Recombinant human Flt3 ligand/Flt3L protein (ab237554)

Recombinant human Flt3 ligand/Flt3L protein (ab237554)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 97% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, HPLC, SDS-PAGE

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Description

  • Product name

    Recombinant human Flt3 ligand/Flt3L protein
    See all Flt3 ligand/Flt3L proteins and peptides
  • Biological activity

    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human AML5 cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0x106 IU/mg.

  • Purity

    > 97 % SDS-PAGE.
    and >97% by HPLC.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    P49771
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      TQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRL VLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTN ISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEA TAPTA
    • Predicted molecular weight

      18 kDa including tags
    • Amino acids

      27 to 181
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab237554 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        HPLC

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        Constituent: PBS

        0.2 µm filtered PBS.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      General Info

      • Alternative names

        • FL
        • Flt 3 ligand
        • Flt 3L
        • Flt3 L
        • FLT3 LG
        • Flt3 ligand
        • Flt3L
        • FLT3L_HUMAN
        • Flt3lg
        • Fms related tyrosine kinase 3 ligand
        • Fms-related tyrosine kinase 3 ligand
        • SL cytokine
        see all
      • Function

        Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
      • Cellular localization

        Secreted and Cell membrane.
      • Target information above from: UniProt accession P49771 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Images

    • SDS-PAGE - Recombinant human Flt3 ligand/Flt3L protein (ab237554)
      SDS-PAGE - Recombinant human Flt3 ligand/Flt3L protein (ab237554)

      SDS-PAGE analysis of ab237554.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab237554? Please let us know so that we can cite the reference in this datasheet.

    ab237554 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • FL
      • Flt 3 ligand
      • Flt 3L
      • Flt3 L
      • FLT3 LG
      • Flt3 ligand
      • Flt3L
      • FLT3L_HUMAN
      • Flt3lg
      • Fms related tyrosine kinase 3 ligand
      • Fms-related tyrosine kinase 3 ligand
      • SL cytokine
      see all
    • Function

      Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
    • Cellular localization

      Secreted and Cell membrane.
    • Target information above from: UniProt accession P49771 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant human Flt3 ligand/Flt3L protein (ab237554)
      SDS-PAGE - Recombinant human Flt3 ligand/Flt3L protein (ab237554)

      SDS-PAGE analysis of ab237554.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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