Recombinant Human FGF19 protein (ab50132)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Suitable for: SDS-PAGE, Functional Studies
-
Product name
Recombinant Human FGF19 protein
See all FGF19 proteins and peptides -
Purity
> 95 % SDS-PAGE.
Greater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per µg (1EU/µg). -
Endotoxin level
Expression system
Escherichia coliProtein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
Associated products
-
Related Products
Specifications
Our Abpromise guarantee covers the use of ab50132 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
SDS-PAGE
Functional Studies
-
Form
Lyophilized -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 0.44% Sodium chloride, 0.064% Tris
-
ReconstitutionCentrifuge the vial prior to opening. Reconstitute in 5-10 mM Sodium Phosphate, pH 8.0 to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use. Repeated freeze thaw cycles will result in some loss of activity.
General Info
-
Alternative names
- FGF 19
- FGF-19
- FGF15
see all -
Function
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB. -
Tissue specificity
Expressed in fetal brain, cartilage, retina, and adult gall bladder. -
Sequence similarities
Belongs to the heparin-binding growth factors family. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab50132 has not yet been referenced specifically in any publications.
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 0.44% Sodium chloride, 0.064% Tris
-
ReconstitutionCentrifuge the vial prior to opening. Reconstitute in 5-10 mM Sodium Phosphate, pH 8.0 to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use. Repeated freeze thaw cycles will result in some loss of activity.
