Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Escherichia coli
Endotoxin level:

Product name

Recombinant Human Eotaxin 2 protein
See all Eotaxin 2 proteins and peptides
Biological activity

Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml.
Endotoxin level
Expression system

Escherichia coli
Protein length

Full length protein
Animal free

No
Nature

Recombinant
- Species
  
  Human
- Sequence
  
  VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
- Predicted molecular weight
  
  13 kDa

Our Abpromise guarantee covers the use of ab9834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Form

Lyophilized
Additional notes

The biological activity of this product is determined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 50.0-100.0 ng/ml.
Concentration information loading...

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Reconstitution

For lot specific reconstitution information please contact our Scientific Support Team.

Alternative names
- C C motif chemokine 24
- C-C motif chemokine 24
- CCL24
- CCL24_HUMAN
- Chemokine CC Motif Ligand 24
- CK beta 6
- CK-beta-6
- Ckb6
- Eosinophil chemotactic protein 2
- Eotaxin-2
- MPIF 2
- MPIF-2
- MPIF2
- Myeloid progenitor inhibitory factor 2
- SCYA24
- Small inducible cytokine A24
- Small inducible cytokine subfamily A (Cys-Cys) member 24
- Small-inducible cytokine A24
see all
Function

Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
Tissue specificity

Activated monocytes and activated T lymphocytes.
Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.
Post-translational
modifications

N-glycosylated.
Cellular localization

Secreted.
Target information above from: UniProt accession O00175 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheet

Publishing research using ab9834? Please let us know so that we can cite the reference in this datasheet.

ab9834 has not yet been referenced specifically in any publications.

Alternative names
- C C motif chemokine 24
- C-C motif chemokine 24
- CCL24
- CCL24_HUMAN
- Chemokine CC Motif Ligand 24
- CK beta 6
- CK-beta-6
- Ckb6
- Eosinophil chemotactic protein 2
- Eotaxin-2
- MPIF 2
- MPIF-2
- MPIF2
- Myeloid progenitor inhibitory factor 2
- SCYA24
- Small inducible cytokine A24
- Small inducible cytokine subfamily A (Cys-Cys) member 24
- Small-inducible cytokine A24
see all
Function

Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
Tissue specificity

Activated monocytes and activated T lymphocytes.
Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.
Post-translational
modifications

N-glycosylated.
Cellular localization

Secreted.
Target information above from: UniProt accession O00175 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt