Recombinant Human CYP2D6 protein (His tag) (ab275567)
Key features and details
- Expression system: Escherichia coli
- Endotoxin level:
- Tags: His-T7 tag N-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human CYP2D6 protein (His tag) -
Purity
>90% by SDS-PAGE. -
Endotoxin level
Expression system
Escherichia coliAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
LAGKV LRFQKAFLTQ LDELLTEHRM TWDPAQPPRD LTEAFLAEME KAKGNPESSF NDENLRIVVA DLFSAGMVTT STTLAWGLLL MILHPDVQRR VQQEIDDVIG QVRRPEMGDQ AHMPYTTAVI HEVQRFGDIV PLGVTHMTSR DIEVQGFRIP KGTTLITNLS SVLKDEAVWE KPFRFHPEHF LDAQGHFVKP EAFLPFSAGR RACLGEPLAR MELFLFFTSL LQHFSFSVPT GQ -
Predicted molecular weight
56 kDa -
Amino acids
236 to 472 -
Tags
His-T7 tag N-Terminus
Specifications
Our Abpromise guarantee covers the use of ab275567 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.24% Tris, 0.87% Sodium chloride, 0.01% Sarkosyl, 5% Trehalose, 0.05% Proclin 300, 0.02% DTT, 0.03% EDTA -
ReconstitutionReconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
General Info
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Alternative names
- Cholesterol 25-hydroxylase
- CP2D6_HUMAN
- CPD6
see all -
Function
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. -
Sequence similarities
Belongs to the cytochrome P450 family. -
Cellular localization
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human CYP2D6 protein (His tag) (ab275567)
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab275567 has not yet been referenced specifically in any publications.
Preparation and Storage
- Cholesterol 25-hydroxylase
- CP2D6_HUMAN
- CPD6
Images
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SDS-PAGE - Recombinant Human CYP2D6 protein (His tag) (ab275567)