Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human CYP2D6 protein (His tag) (ab275567)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Tags: His-T7 tag N-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human CYP2D6 protein (His tag)

  • Purity

    >90% by SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P10635

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      LAGKV LRFQKAFLTQ LDELLTEHRM TWDPAQPPRD LTEAFLAEME KAKGNPESSF NDENLRIVVA DLFSAGMVTT STTLAWGLLL MILHPDVQRR VQQEIDDVIG QVRRPEMGDQ AHMPYTTAVI HEVQRFGDIV PLGVTHMTSR DIEVQGFRIP KGTTLITNLS SVLKDEAVWE KPFRFHPEHF LDAQGHFVKP EAFLPFSAGR RACLGEPLAR MELFLFFTSL LQHFSFSVPT GQ

    • Predicted molecular weight

      56 kDa

    • Amino acids

      236 to 472

    • Tags

      His-T7 tag N-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab275567 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.24% Tris, 0.87% Sodium chloride, 0.01% Sarkosyl, 5% Trehalose, 0.05% Proclin 300, 0.02% DTT, 0.03% EDTA

    • Reconstitution
      Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

    General Info

    • Alternative names

      • Cholesterol 25-hydroxylase
      • CP2D6_HUMAN
      • CPD6
      • CYP2D
      • CYP2D6
      • CYP2D7AP
      • CYP2D7BP
      • CYP2D7P2
      • CYP2D8P2
      • CYP2DL1
      • CYPIID6
      • Cytochrome P450 2D6
      • Cytochrome P450 DB1
      • Cytochrome P450 family 2 subfamily D member 6
      • Cytochrome P450 family 2 subfamily D polypeptide 6
      • Cytochrome P450-DB1
      • Debrisoquine 4 hydroxylase
      • Debrisoquine 4-hydroxylase
      • Flavoprotein linked monooxygenase
      • Microsomal monooxygenase
      • P450 DB1
      • P450C2D
      • P450DB1
      • Xenobiotic monooxygenase
      see all

    • Function

      Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.

    • Sequence similarities

      Belongs to the cytochrome P450 family.

    • Cellular localization

      Endoplasmic reticulum membrane. Microsome membrane.
    • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human CYP2D6 protein (His tag) (ab275567)
    SDS-PAGE - Recombinant Human CYP2D6 protein (His tag) (ab275567)

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab275567? Please let us know so that we can cite the reference in this datasheet.

ab275567 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Cholesterol 25-hydroxylase
  • CP2D6_HUMAN
  • CPD6

Images

  • SDS-PAGE - Recombinant Human CYP2D6 protein (His tag) (ab275567)
    SDS-PAGE - Recombinant Human CYP2D6 protein (His tag) (ab275567)

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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