Recombinant Human CRTAM protein (Tagged) (Biotin) (ab271475)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 86% SDS-PAGE
- Tags: Avi tag C-Terminus, Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human CRTAM protein (Tagged) (Biotin)
See all CRTAM proteins and peptides -
Purity
>= 86 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
SLTNHTETIT VEEGQTLTLK CVTSLRKNSS LQWLTPSGFT IFLNEYPALK NSKYQLLHHS ANQLSITVPN VTLQDEGVYK CLHYSDSVST KEVKVIVLAT PFKPILEASV IRKQNGEEHV VLMCSTMRSK PPPQITWLLG NSMEVSGGTL HEFETDGKKC NTTSTLIIHT YGKNSTVDCI IRHRGLQGRK LVAPFRFEDL VTDEETASDA LERNSLSSQD PQQPTSTVSV TEDSSTSEID KEEKEQTTQD PDLTTEANPQ YLGLARKKS -
Predicted molecular weight
59 kDa including tags -
Amino acids
18 to 286 -
Tags
Avi tag C-Terminus , Fc tag C-Terminus -
Additional sequence information
Fc region of Human IgG1. Genbank: NM_019604
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Conjugation
Biotin
Preparation and Storage
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Alternative names
- CD355
- Class I MHC restricted T cell associated molecule
- Class-I MHC-restricted T-cell-associated molecule
see all -
Function
Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. -
Tissue specificity
In the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. Strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in Purkinje neurons in cerebellum. Expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues. -
Sequence similarities
Belongs to the nectin family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human CRTAM protein (Tagged) (Biotin) (ab271475)SDS-PAGE analysis of ab271475.
