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Recombinant human CCNO protein (Active) (ab177582)

Recombinant human CCNO protein (Active) (ab177582)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Baculovirus infected Sf9 cells
  • Purity: > 90% SDS-PAGE
  • Active: Yes
  • Tags: proprietary tag N-Terminus, proprietary tag N-Terminus
  • Suitable for: Functional Studies, SDS-PAGE, WB

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Description

  • Product name

    Recombinant human CCNO protein (Active)
    See all CCNO proteins and peptides
  • Biological activity

    The specific activity of Cdk2/ Cyclin O was determined to be 46 nmol/min/mg.

  • Purity

    > 90 % SDS-PAGE.
    Assessed by densitometry.
  • Expression system

    Baculovirus infected Sf9 cells
  • Accession

    P24941
    P22674
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Amino Acid Sequence 1

    • Species

      Human
    • Sequence

      MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIR EISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIP LPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR AFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRR ALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSK VVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
    • Predicted molecular weight

      58 kDa including tags
    • Amino acids

      1 to 298
    • Tags

      proprietary tag N-Terminus
    • Additional sequence information

      NM_001798
    • Amino Acid Sequence 2

    • Species

      Human
    • Sequence

      MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCP LPGDSGICDL FESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTF RDYGQSCYAFRKAQESHFHPRE ALARQPQVTAESRCKLLSWLIPVHRQ FGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGV TSLLIACKQVEVHP PRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF TH ARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALAD RMLRVSRP VDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQIC EKCSLPPSSK
    • Predicted molecular weight

      68 kDa including tags
    • Amino acids

      1 to 350
    • Tags

      proprietary tag N-Terminus
    • Additional sequence information

      NM_021147

Preparation and Storage

  • Alternative names

    • CCNO
    • CCNO_HUMAN
    • CCNU
    • Cyclin domain containing
    • Cyclin like uracil DNA glycosylase
    • Cyclin O
    • Cyclin U
    • Cyclin-O
    • DGU
    • EC 3.2.2.
    • UDG2
    • UNG2
    • Uracil DNA glycolylase 2
    • Uracil DNA glycosylase cyclin like
    see all
  • Sequence similarities

    Belongs to the cyclin family.
  • Developmental stage

    Maximum levels during G(1) phase. Levels decrease through S and G(2) phases.
  • Target information above from: UniProt accession P22674 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • Functional Studies - Recombinant human CCNO protein (Active) (ab177582)
    Functional Studies - Recombinant human CCNO protein (Active) (ab177582)
    The specific activity of CCNO (ab177582) was determined to be 43.8 nmol/min/mg as per activity assay protocol
  • SDS-PAGE - Recombinant human CCNO protein (Active) (ab177582)
    SDS-PAGE - Recombinant human CCNO protein (Active) (ab177582)
    SDS PAGE analysis of ab177582
  • SDS-PAGE - Recombinant human CCNO protein (Active) (ab177582)
    SDS-PAGE - Recombinant human CCNO protein (Active) (ab177582)
    SDS PAGE analysis of ab177582
  • Functional Studies - Recombinant human CCNO protein (Active) (ab177582)
    Functional Studies - Recombinant human CCNO protein (Active) (ab177582)

    The specific activity of Cdk2/ Cyclin O was determined to be 46 nmol/min/mg.

  • SDS-PAGE - Recombinant human CCNO protein (Active) (ab177582)
    SDS-PAGE - Recombinant human CCNO protein (Active) (ab177582)

    SDS-PAGE analysis of ab177852 which was determined to be >90% pure by densitometry. Cdk2 is approximately 58 kDa and Cyclin O is approximately 68 kDa.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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