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Signal Transduction Growth Factors/Hormones EGF

Recombinant Human BTC protein (ab276470)

Recombinant Human BTC protein (ab276470)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: Fc tag C-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human BTC protein
    See all BTC proteins and peptides
  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    P35070
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MDRAARCSGA SSLPLLLALA LGLVILHCVV ADGNSTRSPE TNGLLCGDPE ENCAATTTQS KRKGHFSRCP KQYKHYCIKG RCRFVVAEQT PSCVCDEGYI GARCERVDLF Y
    • Predicted molecular weight

      36 kDa including tags
    • Molecular weight information

      The recombinant human BTC/Fc is a disulfide-linked homodimer. The reduced monomer comprises 321 amino acids and has a predicted molecular mass of 36 kDa. The apparent molecular mass of the protein is approximately 43-46 kDa in SDS-PAGE under reducing conditions.
    • Amino acids

      1 to 111
    • Tags

      Fc tag C-Terminus
    • Additional sequence information

      Fc region of human IgG1.Predicted N-terminus: Asp 32.
  • Specifications

    Our Abpromise guarantee covers the use of ab276470 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • Betacellulin
      • Betacellulin precursor
      • BTC
      • BTC_HUMAN
      • OTTHUMP00000160600
      • OTTHUMP00000219057
      • Probetacellulin
      see all
    • Function

      Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors.
    • Tissue specificity

      Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
    • Sequence similarities

      Contains 1 EGF-like domain.
    • Cellular localization

      Cell membrane and Secreted > extracellular space.
    • Target information above from: UniProt accession P35070 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant Human BTC protein (ab276470)
    SDS-PAGE - Recombinant Human BTC protein (ab276470)
    SDS-PAGE analysis of ab276470

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276470? Please let us know so that we can cite the reference in this datasheet.

    ab276470 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Betacellulin
    • Betacellulin precursor
    • BTC

    Images

    • SDS-PAGE - Recombinant Human BTC protein (ab276470)
      SDS-PAGE - Recombinant Human BTC protein (ab276470)
      SDS-PAGE analysis of ab276470

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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