Recombinant human BTC protein (ab200256)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: SDS-PAGE, HPLC, Functional Studies
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Product name
Recombinant human BTC protein
See all BTC proteins and peptides -
Biological activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.
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Purity
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Endotoxin level
Expression system
Escherichia coliAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY -
Predicted molecular weight
8 kDa -
Amino acids
32 to 111 -
Additional sequence information
This product is for the mature, full length Betacellulin protein from aa 32 to 111. The signal peptide is not included
Associated products
Specifications
Our Abpromise guarantee covers the use of ab200256 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
HPLC
Functional Studies
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Form
Lyophilized -
Additional notes
Protein previously labeled as Betacellulin.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS
Lyophilized from a 0.2 um filtered concentrated solution.This product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionReconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL
General Info
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Alternative names
- Betacellulin
- Betacellulin precursor
- BTC
see all -
Function
Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors. -
Tissue specificity
Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. -
Sequence similarities
Contains 1 EGF-like domain. -
Cellular localization
Cell membrane and Secreted > extracellular space. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab200256 has not yet been referenced specifically in any publications.
Preparation and Storage
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Alternative names
- Betacellulin
- Betacellulin precursor
- BTC
see all -
Function
Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors. -
Tissue specificity
Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. -
Sequence similarities
Contains 1 EGF-like domain. -
Cellular localization
Cell membrane and Secreted > extracellular space. - Information by UniProt