Recombinant human BTC protein (ab123846)
Key features and details
- Expression system: Escherichia coli
- Purity: > 97% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, Functional Studies, SDS-PAGE
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Product name
Recombinant human BTC protein
See all BTC proteins and peptides -
Biological activity
The ED50, calculated by the dose-dependant proliferation of murine BALBC 3T3 cells (measured by 3H-thymidine uptake) is 2.0 ×107IU/mg. -
Purity
> 97 % SDS-PAGE.
ab123846 was purified by proprietary chromatographic techniques. Purity is greater than 97% as determined by HPLC and SDS-PAGE. -
Expression system
Escherichia coli -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
DGNSTRSPETNGLLCGDPEENCAATTTQSKRKGHFSRCPKQYKHYCIKGR CRFVVA EQTPSCVCDEGYIGARCERVDLFY -
Predicted molecular weight
9 kDa -
Amino acids
32 to 111
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Preparation and Storage
-
Alternative names
- Betacellulin
- Betacellulin precursor
- BTC
see all -
Function
Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors. -
Tissue specificity
Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. -
Sequence similarities
Contains 1 EGF-like domain. -
Cellular localization
Cell membrane and Secreted > extracellular space. - Information by UniProt
