Recombinant Human BCMA protein (Tagged) (Biotin) (ab269984)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 73% SDS-PAGE
- Tags: Avi tag C-Terminus, Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human BCMA protein (Tagged) (Biotin)
See all BCMA proteins and peptides -
Purity
> 73 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVK GTNA -
Predicted molecular weight
34 kDa including tags -
Actual molecular weight
37 kDa including tags -
Molecular weight information
34 kDa + Glycans -
Amino acids
1 to 54 -
Tags
Avi tag C-Terminus , Fc tag C-Terminus -
Additional sequence information
a.a. 1-54 fused to Fc region of Human IgG1. NM_001192
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Conjugation
Biotin
Preparation and Storage
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Alternative names
- B cell maturation antigen
- B cell maturation factor
- B cell maturation protein
see all -
Function
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. -
Tissue specificity
Expressed in mature B-cells, but not in T-cells or monocytes. -
Involvement in disease
Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2. -
Sequence similarities
Contains 1 TNFR-Cys repeat. -
Cellular localization
Cell membrane. Endomembrane system. Perinuclear Golgi-like structures. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human BCMA protein (Tagged) (Biotin) (ab269984)
SDS-PAGE analysis of 4 µg ab269984 (Lane 1). 4-20% gel with Coomassie staining.