Recombinant human 4-1BBL protein (Active) (ab271406)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 73% SDS-PAGE
- Active: Yes
- Tags: His tag N-Terminus, Avi tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant human 4-1BBL protein (Active)
See all 4-1BBL proteins and peptides -
Biological activity
Assay was performed using a CD137[Biotinylated]:CD137L Inhibitor Screening Assay Kit with CD137 [Biotin] enzyme titrated from 40 ng/rxn – 0 ng/rxn.
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Purity
>= 73 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
ACPWAVSGAR ASPGSAASPR LREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE -
Predicted molecular weight
25 kDa including tags -
Amino acids
50 to 254 -
Tags
His tag N-Terminus , Avi tag N-Terminus -
Additional sequence information
Genbank: NM_003811
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Preparation and Storage
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Alternative names
- 4 1BB L
- 4 1BB ligand
- 4 1BBL
see all -
Function
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. -
Tissue specificity
Expressed in brain, placenta, lung, skeletal muscle and kidney. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Cellular localization
Membrane. - Information by UniProt
Images
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Functional Studies - Recombinant Human 4-1BBL protein (Tagged) (ab271406)
Functional analysis of ab271406.
CD137 = 4-1BBL.
Assay was performed using a CD137[Biotinylated]:CD137L Inhibitor Screening Assay Kit with CD137 [Biotin] enzyme titrated from 40 ng/rxn – 0 ng/rxn.
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SDS-PAGE - Recombinant Human 4-1BBL protein (Tagged) (ab271406)SDS-PAGE analysis of 4 μg of ab271406.