Human Granulysin ELISA Kit (ab213787)
Key features and details
- Sensitivity: 10 pg/ml
- Range: 31.2 pg/ml - 2000 pg/ml
- Sample type: Cell culture supernatant, Cell Lysate, EDTA Plasma, Hep Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components Identifier 1 x 96 tests ABC Diluent Buffer Blue Cap 1 x 12ml Adhesive Plate Seal 4 units Antibody Diluent Buffer Green Cap 1 x 12ml Anti-Human Granulysin Coated Microplate (12 x 8 wells) 1 unit Avidin-Biotin-Peroxidase Complex (ABC) 1 x 100µl Biotinylated Anti-Human Granulysin Antibody 1 x 130µl Lyophilized Recombinant Human Granulysin Standard 2 vials Sample Diluent Buffer Green Cap 1 x 30ml TMB Color Developing Agent Black Cap 1 x 10ml TMB Stop Solution Yellow Cap 1 x 10ml -
Research areas
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Function
Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. -
Tissue specificity
Expressed in natural killer and T-cells. -
Sequence similarities
Contains 1 saposin B-type domain. -
Post-translational
modificationsA 9 kDa form is produced by proteolytic processing of a 15 kDa protein. -
Cellular localization
Secreted. Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation. - Information by UniProt
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Alternative names
- 519
- D2S69E
- GNLY
see all -
Database links
- Entrez Gene: 10578 Human
- Omim: 188855 Human
- SwissProt: P22749 Human
- Unigene: 105806 Human