• Product name

  Recombinant human 4-1BBL protein
  See all 4-1BBL proteins and peptides

• Biological activity

  Determined by the dose-dependent stimulation of IL-8 production by human PBMC. The ED₅₀ for this effect is 5-10 ng/ml.
  Please Note: Results may vary with PBMC donors.

• Purity

  > 95 % SDS-PAGE.
  Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  

• Expression system

  Escherichia coli

• Protein length

  Protein fragment

• Animal free

  No

• Nature

  Recombinant

• • Species

    Human

  • Sequence

    MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE

  • Amino acids

    71 to 254

• Alternative names

  • 4 1BB L
  • 4 1BB ligand
  • 4 1BBL

  • 4-1BB ligand
  • 4-1BBL
  • Cd137l
  • Cd157l
  • Homolog of mouse 4 1BB L
  • Homolog of mouse 4 1BBL
  • ILA ligand (TNF related)
  • Ly63l
  • Receptor 4 1BB ligand
  • TNF superfamily member 9
  • TNFL9_HUMAN
  • Tnfsf9
  • TNLG5A
  • Tumor necrosis factor (ligand) superfamily member 9
  • Tumor necrosis factor ligand 5A
  • Tumor necrosis factor ligand superfamily member 9
  • Tumor necrosis factor superfamily member 9

  see all

• Function

  Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

• Tissue specificity

  Expressed in brain, placenta, lung, skeletal muscle and kidney.

• Sequence similarities

  Belongs to the tumor necrosis factor family.

• Cellular localization

  Membrane.

• Target information above from: UniProt accession P41273 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt